Three herbal medicine recipes were tried on the animal model of diet induced hypercholesterolemia to screen for the lipid-lowering effect. The recipes adopted were based on the prescription for atherosclerosis-relate symptoms by folk-medicine
practioners. Hyperlipidemia was induced in rats by giving the high lipid/cholesterol diet for 7 days. Then, the recipes started with the normal diet. Blood was sampled at 1,2,3 and 5 week-points of the treatment, and levels of total cholesterol,
triglyceride, high density lipoprotein and lower density lipoprotein were measured, Dae-shiho-tang decreased total cholesterol level significantly. Hwangryun-haedoktang and Samhwang-sasim-tang slightly decreased total cholesterol level, although
it
was
not statistically significant.
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